ApoB · 1 in 5 people with normal cholesterol carry hidden heart riskFITNESS · each level of aerobic capacity lowers mortality 11 to 15 percentSTRENGTH · the weakest 20% by grip strength double their risk of dyingMUSCLE · after 60, the body needs more protein, not lessLONGEVITY · partner labs live: measure, prevent and saveApoB · 1 in 5 people with normal cholesterol carry hidden heart riskFITNESS · each level of aerobic capacity lowers mortality 11 to 15 percentSTRENGTH · the weakest 20% by grip strength double their risk of dyingMUSCLE · after 60, the body needs more protein, not lessLONGEVITY · partner labs live: measure, prevent and saveApoB · 1 in 5 people with normal cholesterol carry hidden heart riskFITNESS · each level of aerobic capacity lowers mortality 11 to 15 percentSTRENGTH · the weakest 20% by grip strength double their risk of dyingMUSCLE · after 60, the body needs more protein, not lessLONGEVITY · partner labs live: measure, prevent and save
Health Journal · Washington D.C.No. 004 · Sunday, June 14, 2026
Health Journal·Es Posible·Live longer, live better
Issue No. 004 · Your health, in numbersThere is a number your normal cholesterol hides from you.
The best health news of the year is not a pill: it is learning to measure what truly predicts your life. Four numbers, and the tool to have them all.
1 in 5
with normal LDL and hidden risk
11-15%
lower mortality per fitness level
2x
higher risk with low strength
60+
biomarkers in Longevity
01Heart · The best news
Best news of the dayEuropean Heart Journal (Sniderman et al.), 2025 · UK Biobank, 2025 · AHA, 2026
ApoB: the number your normal cholesterol hides
Your cholesterol test can look fine and your heart still be at risk. One number reveals it better than the LDL we have always used.
A 2025 review in the European Heart Journal, pooling nearly 600,000 people, reached a blunt conclusion: ApoB —which counts the number of artery-clogging particles, not just the cholesterol inside them— predicts heart attacks better than LDL. In the nine studies that compared them head to head, ApoB won all nine. The American Heart Association points the same way.
What matters for you: about 1 in 5 people with a normal LDL have high ApoB and a heart risk the traditional test misses. The danger slips by precisely in those who think they are safe, especially with metabolic syndrome, diabetes or high triglycerides.
The action is simple: ask that your next test include ApoB (and, if possible, Lp(a), measured once in a lifetime). It is a common blood test. Knowing that number changes decisions: from diet and exercise to whether treatment is worth it. What is not measured cannot be corrected.
02Heart and lungs
Mandsager et al., JAMA Network Open, 2018 · JACC, 2018
Your fitness predicts your life better than almost anything
Cardiorespiratory fitness is one of the strongest predictors of how long you will live. And it improves at any age.
In a Cleveland Clinic study of more than 122,000 people (JAMA Network Open), low aerobic capacity weighed more than smoking, diabetes or high blood pressure, with no ceiling: the fitter you are, the lower the risk. Other work estimates each step up is linked to 11 to 15 percent lower mortality.
You do not need a lab to start. Brisk walking, stairs, dancing or cycling raises fitness. The rule: move at an intensity where you can talk but not sing, most days. If one block is hard today, the goal is that in a month it costs you less.
03Strength
Scientific Reports (NHANES), 2024 · The Lancet, 2015
Your handshake says more than you think
Grip strength is a 10-second test that became a thermometer of aging.
In NHANES data (Scientific Reports), the weakest 20 percent by grip strength had more than double the risk of dying from any cause; over 70, about 80 percent more. The Lancet calls it a simple but powerful predictor of disability and mortality.
It matters because it reflects whole-body muscle, which holds up your independence. And it can be trained: squeeze a ball, carry the groceries on purpose, hang from a bar, use bands and light dumbbells. Two or three times a week is enough to start.
Risk of death by grip strength (NHANES)
The weakest fifth doubles the risk · over 70: +80%
04Muscle and protein
ESPEN, 2014 · Frontiers in Nutrition, 2025 · Nutrients, 2025 · consult your doctor if you have kidney disease
After 60, the body asks for more protein
With age you lose muscle: that is sarcopenia. Protein, with some strength work, is the tool to slow it.
It affects 5 to 13 percent of people in their 60s and up to half of those over 80, and is tied to falls and loss of independence. Yet about 30 percent of men and half of women over 71 eat less protein than they need.
Clinical consensus (ESPEN) recommends at least 1.0 to 1.2 grams per kilo of body weight per day —1.2 to 1.5 if recovering—, spread across 25 to 30 grams per meal. For 70 kilos, that is about 70 to 84 grams a day. Simple sources: eggs, Greek yogurt, chicken, fish, lentils, beans, tofu. Pair it with strength two or three times a week.
◆ Es Posible · Longevity, explainedEverything Longevity measures, prevents and saves you
Longevity by Es Posible is your smart health hub. It brings together in one place more than 60 biomarkers across 12 clinical categories, an electrocardiogram, ultrasounds and discounted consultations. Not a single test: your health, measured, interpreted and tracked over time.
What it measures · 12 categories, 60+ biomarkers
Cardiovascular
ApoB, cholesterol, triglycerides, Lp(a) · your real risk of heart attack and atherosclerosis.
Metabolic
glucose, glycated hemoglobin, insulin · prediabetes and diabetes, years before symptoms.
Inflammation
C-reactive protein and more · the silent inflammation that damages arteries.
Thyroid
TSH, T3, T4 · fatigue, weight, mood and metabolism.
Hormones
testosterone, estrogen, cortisol · energy, libido, bone and mood.
Liver
liver enzymes · fatty liver and early damage.
Kidney
creatinine and filtration · kidney function before it fails.
Blood
complete blood count · anemia, infection, immunity.
Vitamins
vitamin D, B12 and more · deficiencies that steal energy and bone.
Oncologic
screening markers · early signals, including prostate.
Nutrition / iron
ferritin and nutritional status · fatigue and weakened defenses.
Integrated CV risk
your cardiovascular probability calculated from all your data together.
And also
Cardiovascular EKGUltrasoundsDiscounted consultationsHealth simulatorHistory over timeMarker monitoringCalculatorsClinical AI chat
What it prevents
Each category is a disease you can slow if you see it in time: heart attack and atherosclerosis (cardiovascular and ApoB), diabetes (metabolic), kidney and liver damage, thyroid problems, vitamin deficiencies and early signals of cancer. Early detection is not a luxury: it is the difference between fixing a number with habits today, or treating an advanced disease tomorrow.
How it saves you money
Plus
$14.99
USD/mo · most popular
With partner labs now live, you get panels of more than 60 biomarkers, EKG, ultrasounds and consultations at member pricing, tests that separately and at retail cost hundreds of dollars. And the biggest saving is the invisible one: detecting and correcting a high marker in time costs a fraction of what it costs —in money and in life— to treat a heart attack, advanced diabetes or late-stage cancer.
See Longevity plans →
◆ What no one tells you
Today's four numbers share something: they are easy to measure and improve with the same things. ApoB, with diet, exercise and, if needed, treatment. Fitness, by walking fast. Strength, by carrying weight. Muscle, with protein and movement. The medicine that extends life is neither expensive nor mysterious: it is measuring in time and acting. That is why Longevity exists, so you have all those numbers in one place and can see whether you are on track. Measure, move, and measure again.
Measure, don't guess
Longevity by Es Posible is live with partner labs: 60+ biomarkers, EKG, ultrasounds and discounted consultations. Turn your tests into a plan to live longer and better.